Enantioselective Synthesis of Tertiary Nitroalkanes Enabled by Enzyme Catalysis
نویسندگان
چکیده
Key words alkylation - nitronates nitroalkanes α-tertiary amines ‘ene’-reductase (ERED) photoredox catalysis
منابع مشابه
Enantioselective synthesis of tertiary α-chloro esters by non-covalent catalysis
We report an enantioselective approach to tertiary α-chloro esters through the reaction of silyl ketene acetals and N-chlorosuccinimide. The reaction is promoted by a chiral squaramide catalyst, which is proposed to engage both reagents exclusively through non-covalent interactions. Application of the tertiary chloride products in stereospecific substitution reactions is demonstrated.
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ژورنال
عنوان ژورنال: Synfacts
سال: 2023
ISSN: ['1861-194X', '1861-1958']
DOI: https://doi.org/10.1055/s-0042-1751866